AASLD-IDSA Simplified HCV Treatment for Treatment-Naive Adults With Compensated Cirrhosis

Zusammenfassung

SimpliĮed HCV Treatment Algorithm for Treatment-Naive Adults With Compensated Cirrhosis WHO IS NOT ELIGIBLE FOR SIMPLIFIED TREATMENT WHO IS ELIGIBLE FOR SIMPLIFIED TREATMENT PaƟents who have any of the following characterisƟcs: • Current or prior episode of decompensated cirrhosis, deĮned as Child-TurcoƩe-Pugh (CTP) score ≥7 (ascites, hepaƟc encephalopathy, total bilirubin >2.0 mg/dL, albumin ≤3.5 g/dL, or INR ≥1.7) • Prior hepaƟƟs C treatment • End-stage renal disease (i.e., eGFR <30

Kerninformationen

SimpliĮed HCV Treatment Algorithm for Treatment-Naive Adults With Compensated Cirrhosis RECOMMENDED REGIMENS* ON-TREATMENT MONITORING Genotype 1-6: Glecaprevir (300 mg) / pibrentasvir (120 mg) taken with food for a duraƟon of 8 weeks Genotype 1, 2, 4, 5, or 6: Sofosbuvir (400 mg)/velpatasvir...

Monitoring for hypoglycemia is recommended. • Inform paƟents taking warfarin of the potenƟal for changes in their anƟcoagulaƟon status. Monitoring INR for subtherapeuƟc anƟcoagulaƟon is recommended. • An in-person or telehealth/phone visit may be scheduled, if needed, for paƟent support, asses...

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