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PLOS Neglected Tropical Diseases2025EN

Risk factors and control of Opisthorchis viverrini in the Lower Mekong Basin: A systematic review

Zusammenfassung

PLoS Negl Trop Dis. 2025 Dec 11;19(12):e0013790. doi: 10.1371/journal.pntd.0013790 Risk factors and control of Opisthorchis viverrini in the Lower Mekong Basin: A systematic review Suji Y O’Connor Suji Y O’Connor 1National Centre for Epidemiology and Population Health, Australian National University, Acton, Australian Capital Territory, Australia Conceptualization, Investigation, Writing – original draft, Writing – review & editing Find articles by Suji Y O’Connor 1,*, Mary Lorraine Mationg Mary

Kerninformationen

PMC Copyright notice PMCID: PMC12698015 PMID: 41379847 Abstract Background Opisthorchis viverrini (OV) is a major public health concern in the Lower Mekong Basin. This study aimed to synthesize all field-based empirical research examining risk factors and control strategies for OV in the Lower Mekon...
OV is endemic to the Lower Mekong Basin –a region in Southeast Asia that includes Northeast Thailand, Lao People’s Democratic Republic, Southern Vietnam, and Cambodia– and is estimated to affect over 12 million people in the region. We conducted a systematic review of all field-based literature on O...
The difficulties of OV detection and treatment are further complicated by OV’s multistage lifecycle involving two intermediate hosts (aquatic snails, cyprinid fish) and one definitive host (humans and other fish-eating mammals), as shown in Fig 1 [12,15]. While animal research is limited, studies in...
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