Use of a Novel Surgical Irrigant Significantly Reduces Rate of Infection in Primary Hip and Knee Arthroplasty at 1 year

Zusammenfassung

Arthroplast Today. 2025 Nov 26;36:101907. doi: 10.1016/j.artd.2025.101907 Use of a Novel Surgical Irrigant Significantly Reduces Rate of Infection in Primary Hip and Knee Arthroplasty at 1 year Ravi K Bashyal Ravi K Bashyal, MD aDepartment of Orthopaedic Surgery, Endeavor Health Orthopaedic & Spine Institute, Skokie, IL, USA Find articles by Ravi K Bashyal a,∗, Avinash Inabathula Avinash Inabathula, MD aDepartment of Orthopaedic Surgery, Endeavor Health Orthopaedic & Spine Institute, Skokie, IL,

Kerninformationen

The control group of 1045 patients received a dilute povidone-iodine soak followed by saline rinse. The experimental group of 1042 patients received the new irrigant (XPerience (XP)) without secondary rinse. The International Consensus Meeting 2018 recommended algorithm and criteria were used to dia...

However, the Food and Drug Administration (FDA) recently issued a label change request to manufacturers and a reminder to health-care professionals stating, “If a product does not state “sterile” on the label, health-care professionals should be aware that they are using a nonsterile product” [10,11...

Citric acid is approved for use in endodontic surgery as a bone surface cleanser and has shown no cytotoxicity or decalcification at the concentrations present in XP [[21], [22], [23], [24], [25]]. Citric acid’s antibacterial properties and induction of transforming growth factor-β1 release have als...

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